Vekovia · Pomegranate
Pasteurised Akkermansia muciniphila + freeze-dried European pomegranate + vitamin C. The longevity-leaning pairing.
Vitamin C contributes to the protection of cells from oxidative stress.
The berry, the bacterium, and the molecule mitochondrial research is built on.
What it is
A daily capsule that pairs:
- Pasteurised Akkermansia muciniphila — the EU-authorised Novel Food strain.
- Freeze-dried European pomegranate — rich in ellagitannins (primarily punicalagin), the compounds gut microbes convert into urolithin A.
- A standardised pomegranate polyphenol extract — for a consistent ellagitannin dose.
- Vitamin C, which contributes to the protection of cells from oxidative stress.
The science, in brief
Pomegranate ellagitannins have been shown to stimulate the growth of Akkermansia muciniphila in vivo (Henning et al., 2017). The same ellagitannins are the raw material gut microbes turn into urolithin A — a molecule studied in randomised human trials for mitochondrial and cellular health and muscle function (Andreux et al., 2019; Singh et al., 2022), and shown to support gut-barrier integrity via the Nrf2 pathway (Singh et al., 2019). A 2024 systematic review summarised the human urolithin A evidence (Kuerec et al., 2024).
The full pomegranate–Akkermansia–urolithin A trail is mapped in the science hub.
How to take it
One capsule daily with water. Not suitable for children under 12, pregnant or breastfeeding women. Do not exceed the recommended daily dose. A food supplement is not a substitute for a varied, balanced diet.
References
- Henning SM et al. Pomegranate ellagitannins stimulate the growth of Akkermansia muciniphila in vivo. Anaerobe 2017. PMID 27940244. DOI · PubMed
- Ryu D et al. Urolithin A induces mitophagy and prolongs lifespan in C. elegans and increases muscle function in rodents. Nat Med 2016. PMID 27400265. DOI · PubMed
- Andreux PA et al. The mitophagy activator urolithin A is safe and induces a molecular signature of improved mitochondrial and cellular health in humans. Nat Metab 2019. PMID 32694802. DOI · PubMed
- Singh A et al. Urolithin A improves muscle strength, exercise performance, and biomarkers of mitochondrial health in a randomized trial in middle-aged adults. Cell Rep Med 2022. PMID 35584623. DOI · PubMed
- Singh R et al. Enhancement of the gut barrier integrity by a microbial metabolite through the Nrf2 pathway. Nat Commun 2019. PMID 30626868. DOI · PubMed
- Kuerec AH et al. Targeting aging with urolithin A in humans: a systematic review. Ageing Res Rev 2024. PMID 39002645. DOI · PubMed