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Journal

The science of Akkermansia, in plain English.

Mechanism · 8 min read

Why we don't make claims (and why that's the point)

Most supplement brands promise outcomes. We describe research and stop there. Here's the EU rulebook behind that choice — and why restraint, not bravado, is the strategy we chose on purpose.

Longevity · 8 min read

Urolithin A, explained

Your body can't make urolithin A on its own. Your gut microbes make it from the polyphenols in pomegranate and berries. Here's what it is, how it's made, and what the human trials actually show.

Gut · 7 min read

The mucin layer: your gut's quiet workhorse

The mucus lining your gut is a two-layer barrier that quietly keeps the inside in. Here's how it works, how Akkermansia helps renew it, and why a healthy barrier matters.

Metabolic · 7 min read

The mouse study that started a field

In 2013, one mouse study turned an obscure gut bacterium into a research field. Here's what Everard and colleagues found — and the metformin clue that arrived alongside it.

Gut · 5 min read

Raspberry and the gut barrier: the everyday one

The gentlest member of the range, built around the gut's mucus lining — where Akkermansia lives, and what it's named for. An honest look at a thinner but real evidence base.

Longevity · 6 min read

The pomegranate trail: from a Mediterranean fruit to a mitochondrial molecule

Pomegranate → Akkermansia → urolithin A. One of the most carefully traced food-to-microbe-to-metabolite pathways in nutrition science, and the reason pomegranate anchors our longevity pairing.

Mechanism · 6 min read

From a Belgian lab to your doorstep: how we source

Three ingredients, traced honestly: the bacterium from the European lab holding the EU Novel Food authorisation, freeze-dried European berries, and no preservatives. Here's the chain.

Mechanism · 7 min read

How freeze-drying works (and why space agencies use it)

Freeze-drying removes water without heat damage, which is exactly why it suits a pasteurised bacterium whose value lives in its surface proteins. Here's the physics, plainly.

Metabolic · 5 min read

Bilberry: the metabolic berry

Why we paired Akkermansia with the wild European bilberry — the small dark berry with two to four times the anthocyanins of a cultivated blueberry, and a place in the metabolic-health literature.

Mechanism · 7 min read

Amuc_1100: the protein doing the work

A single outer-membrane protein from Akkermansia reproduces much of the whole bacterium's effect in mice — which neatly explains why the dead, pasteurised form works at all.

Metabolic · 7 min read

Akkermansia and type 2 diabetes: the 2025 trial in context

In 2025, a human trial extended the Akkermansia research into people with type 2 diabetes. Here's what it found, how it builds on a 2019 proof-of-concept, and why we describe it carefully.

Mechanism · 7 min read

Akkermansia and the immune system: an honest look

Akkermansia keeps appearing in immune research, including a landmark 2018 cancer-immunotherapy study. It's a fascinating, exploratory association — and explicitly not a claim that our supplement does anything to immunity.

Mechanism · 6 min read

What is Akkermansia muciniphila?

A gut bacterium discovered in 2004, named for the mucus layer it lives in — and one of the most-studied microbes in modern metabolic and longevity science.

Metabolic · 6 min read

The pasteurised paradox: why dead bacteria worked better than live ones

In the first human trial of Akkermansia, the pasteurised form outperformed the live one. Here's why non-living bacteria can be the more useful kind — and why the EU authorised exactly that form.

Metabolic · 7 min read

The protein, the receptor, the hormone: Akkermansia and GLP-1

GLP-1 is the hormone behind today's biggest metabolic conversation. In 2021, scientists found that Akkermansia secretes a specific protein that triggers your gut to release it. This is mechanism, not metaphor.